What Is PNC-27 Peptide?
We supply PNC-27 Peptide as a laboratory-grade research compound for pre-clinical and in vitro study settings. PNC-27 Peptide is a p53-derived peptide targeting HDM-2 in cell membranes. Researchers apply it in laboratory and in vitro research settings. We manufacture it to a defined synthesis standard. Importantly, we restrict distribution to qualified researchers and laboratory personnel.
Research Applications
PNC-27 combines a p53-derived sequence with a membrane-penetrating domain. Researchers designed this combination to interact with HDM-2 protein localised in certain cell membranes.
Interest in cellular & longevity research continues to grow within pre-clinical literature. Here, this compound serves as one of several reference materials researchers use to study relevant signalling pathways. Consistency of starting material supports reproducible results, though it forms only one part of a wider experimental design. Researchers should therefore standardise handling procedures alongside sourcing to minimise variability between runs.
Purity, Testing & Quality Assurance
Every production run undergoes independent purity and identity testing, most commonly by HPLC or mass spectrometry, and we provide a Certificate of Analysis on request. This gives laboratories a way to confirm specification before use, which matters most when a study’s findings need replication elsewhere. We keep full batch documentation on file for traceability.
Storage & Reconstitution
This compound ships in lyophilised form. Researchers should reconstitute it just before use with a suitable solvent, such as bacteriostatic water. After reconstitution, the solution loses stability more quickly at room temperature, so we recommend refrigeration and use within a short window. Reconstituting only what a single experiment needs helps avoid unnecessary freeze-thaw cycling, which can degrade peptide integrity over repeated cycles. The unopened, lyophilised form remains more stable when researchers follow the storage conditions on its COA.
Usage Restrictions
This product serves laboratory and in vitro research only. It is not a medicine, and researchers must not use it for human consumption, animal consumption, diagnosis, or therapy. For independent chemical reference data, researchers can consult the PubChem compound database.
Related Research Compounds
Researchers working in Cellular & Longevity Research may also find SS-31 Peptide — Mitochondria-Targeted Tetrapeptide relevant to their study design. It sits alongside this compound in the same category, together with reconstitution supplies for laboratory preparation.


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